EC Number |
Protein Variants |
Reference |
---|
1.3.1.20 | W125Y |
shows a decreased kcat value compared to the wild type enzyme |
684150 |
1.3.1.20 | W254A |
production by site-directed mutagenesis |
684150 |
1.3.1.20 | W254A |
shows a decreased kcat value compared to the wild type enzyme |
684150 |
1.3.1.20 | W254A |
the mutation affects inhibition and substrate affinity |
686023 |
1.3.1.20 | W254Y |
production by site-directed mutagenesis |
684150 |
1.3.1.20 | W254Y |
shows a decreased kcat value compared to the wild type enzyme |
684150 |
1.3.1.20 | Y180F |
site-directed mutagenesis, very low activity |
286127 |
1.3.1.20 | Y55F |
very low dehydrogenase activity |
349250 |
1.3.1.20 | Y55H |
decreased dehydrogenase activity, significant increased in reductase activity |
349250 |