EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    6.3.4.3 | Abortion, Habitual |
23685927 |
Polymorphisms in MTHFR, MTHFD, and PAI-1 and recurrent miscarriage among North Indian women. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
| 6.3.4.3 | Alzheimer Disease |
8053655 |
Chromosomal fragility associated with familial Alzheimer's disease. |
causal interaction
unassigned |
4
0 |
| 6.3.4.3 | Anemia, Megaloblastic |
22108709 |
Update and new concepts in vitamin responsive disorders of folate transport and metabolism. |
causal interaction
unassigned |
4
0 |
| 6.3.4.3 | Atypical Hemolytic Uremic Syndrome |
22108709 |
Update and new concepts in vitamin responsive disorders of folate transport and metabolism. |
causal interaction
unassigned |
4
0 |
| 6.3.4.3 | Carcinogenesis |
17438114 |
Polymorphisms of MTHFD, plasma homocysteine levels, and risk of gastric cancer in a high-risk Chinese population. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
4
1 |
| 6.3.4.3 | Cleft Palate |
26834978 |
Is MTHFD1 polymorphism rs 2236225 (c.1958G>A) associated with the susceptibility of NSCL/P? A systematic review and meta-analysis. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 6.3.4.3 | Colonic Neoplasms |
15013446 |
A novel mitochondrial C1-tetrahydrofolate synthetase is upregulated in human colon adenocarcinoma. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 6.3.4.3 | Colonic Neoplasms |
21156972 |
Mthfd1 is a modifier of chemically induced intestinal carcinogenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
2
0 |
| 6.3.4.3 | Colonic Neoplasms |
33605411 |
Integrated bioinformatics analysis identified MTHFD1L as a potential biomarker and correlated with immune infiltrates in hepatocellular carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
3
1 |
| 6.3.4.3 | Colorectal Neoplasms |
22202336 |
[Prediction of the efficacy of modified FOLFOX6 therapy according to the mRNA levels of thymidylate synthase (TS), excision repair cross-complementing-1 and -2( ERCC-1 and ERCC-2) and methylenetetrahydrofolate dehydrogenase( MTHFD) in the primary lesion of colorectal cancer]. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
3
2 |
