EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    5.2.1.2 | Acidosis, Lactic |
12730618 |
Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
1
0 |
| 5.2.1.2 | Acidosis, Lactic |
16278372 |
Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. |
causal interaction
therapeutic application
unassigned |
4
2
0 |
| 5.2.1.2 | Acidosis, Lactic |
16609361 |
Polymorphisms in the human glutathione transferase zeta promoter. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 5.2.1.2 | Acidosis, Lactic |
22028318 |
Prenatal and postnatal expression of glutathione transferase ? 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate. |
causal interaction
unassigned |
1
0 |
| 5.2.1.2 | Amyotrophic Lateral Sclerosis |
34311603 |
Glutathione S-transferase Omega 2 DD genotype is associated with an increased risk of sporadic amyotrophic lateral sclerosis in Chinese men. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 5.2.1.2 | Breast Neoplasms |
11737895 |
Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 5.2.1.2 | Breast Neoplasms |
19859803 |
No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
1
3
0 |
| 5.2.1.2 | Breast Neoplasms |
21823988 |
Susceptibility to Breast Cancer and Three Polymorphisms of GSTZ1. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
1 |
| 5.2.1.2 | Carcinogenesis |
31666108 |
GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. |
causal interaction
unassigned |
4
0 |
| 5.2.1.2 | Carcinoma, Hepatocellular |
26850694 |
GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate. |
causal interaction
ongoing research
unassigned |
4
2
0 |
