EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   4.2.2.8 | Adenocarcinoma |
6884696 |
Sialoglycopeptides obtained from a transplantable rat colorectal adenocarcinoma: a comparison with those from normal colonic mucosa. |
diagnostic usage
ongoing research
unassigned |
3
3
0 |
| 4.2.2.8 | Albuminuria |
18003778 |
Removal of heparan sulfate from the glomerular basement membrane blocks protein passage. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 4.2.2.8 | Albuminuria |
32870819 |
Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis. |
therapeutic application
unassigned |
4
0 |
| 4.2.2.8 | Alzheimer Disease |
1590792 |
Characterization of proteoglycans in Alzheimer's disease fibroblasts. |
unassigned |
0 |
| 4.2.2.8 | Arthritis |
17368052 |
FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer. |
unassigned |
0 |
| 4.2.2.8 | Bone Resorption |
3455630 |
J774A.1 macrophage cell line produces PDGF-like and non-PDGF-like growth factors for bone cells. |
ongoing research
unassigned |
2
0 |
| 4.2.2.8 | Carcinoma |
11573243 |
Ovarian carcinoma cells synthesize both chondroitin sulfate and heparan sulfate cell surface proteoglycans that mediate cell adhesion to interstitial matrix. |
causal interaction
ongoing research
unassigned |
3
4
0 |
| 4.2.2.8 | Carcinoma |
18691882 |
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 4.2.2.8 | Carcinoma, Hepatocellular |
6452448 |
Degradative removal of heparan sulfate from the surface of an ascites hepatoma, AH 66, by heparitinase. |
unassigned |
0 |
| 4.2.2.8 | Corneal Dystrophies, Hereditary |
6969547 |
Abnormal product of corneal explants from patients with macular corneal dystrophy. |
causal interaction
ongoing research
unassigned |
2
1
0 |
