EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.6.4.6 | Adenocarcinoma of Lung |
30431439 |
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2?-mediated tumor progression. |
causal interaction ongoing research unassigned |
3 2 0 |
3.6.4.6 | Alzheimer Disease |
11244216 |
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease. |
unassigned |
0 |
3.6.4.6 | Alzheimer Disease |
31223056 |
MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. |
unassigned |
0 |
3.6.4.6 | Amyotrophic Lateral Sclerosis |
26134898 |
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication. |
causal interaction unassigned |
1 0 |
3.6.4.6 | Amyotrophic Lateral Sclerosis |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction therapeutic application unassigned |
1 1 0 |
3.6.4.6 | Apraxias |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction therapeutic application unassigned |
1 1 0 |
3.6.4.6 | Arthritis, Rheumatoid |
27623077 |
AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts. |
causal interaction ongoing research unassigned |
2 3 0 |
3.6.4.6 | Asthma |
33733641 |
ATP6V0d2 Suppresses Alveoli Macrophage Alternative Polarization and Allergic Asthma via Degradation of PU.1. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 4 1 |
3.6.4.6 | Ataxia |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction therapeutic application unassigned |
1 1 0 |
3.6.4.6 | Bacterial Infections |
11092884 |
Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. |
ongoing research unassigned |
3 0 |