EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.5.1.89 | Thymoma |
14742432 |
Subcellular localization and targeting of N-acetylglucosaminyl phosphatidylinositol de-N-acetylase, the second enzyme in the glycosylphosphatidylinositol biosynthetic pathway. |
ongoing research
unassigned |
3
0 |
| 3.5.1.89 | Trypanosomiasis, African |
12364327 |
Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.5.1.89 | Trypanosomiasis, African |
15817455 |
The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme. |
therapeutic application
unassigned |
4
0 |
| 3.5.1.89 | Trypanosomiasis, African |
22222041 |
Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.5.1.89 | Trypanosomiasis, African |
24589444 |
Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase. |
therapeutic application
unassigned |
1
0 |
| 3.5.1.89 | Trypanosomiasis, African |
26476127 |
In silico drug re-purposing against African sleeping sickness using GlcNAc-PI de-N-acetylase as an experimental target. |
ongoing research
therapeutic application
unassigned |
1
4
0 |
