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Results 1 - 10 of 253 > >>
EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 10213160 Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques. causal interaction
diagnostic usage
ongoing research
unassigned
1
3
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 10786709 Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. unassigned 0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 10833395 Functional human insulin-degrading enzyme can be expressed in bacteria. causal interaction
unassigned
3
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 11102481 Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques. therapeutic application
unassigned
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 11125142 Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. causal interaction
unassigned
3
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 11810277 Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. causal interaction
unassigned
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 12161276 Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. causal interaction
unassigned
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 12507914 Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. causal interaction
unassigned
2
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 12634421 Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. causal interaction
unassigned
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.56Alzheimer Disease 12732730 Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. causal interaction
unassigned
3
0
Results 1 - 10 of 253 > >>