EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B12 | Adenocarcinoma |
17230566 |
Kallikrein 4 is expressed in malignant mesothelioma--further evidence for the histogenetic link between mesothelial and epithelial cells. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 3.4.21.B12 | Adenocarcinoma |
23201139 |
Kallikrein-related peptidase 4 (KLK4) mRNA predicts short-term relapse in colorectal adenocarcinoma patients. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
3
1
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
15235027 |
Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta. |
causal interaction
unassigned |
2
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
16674656 |
Human enamel phenotype associated with amelogenesis imperfecta and a kallikrein-4 (g.2142G>A) proteinase mutation. |
causal interaction
ongoing research
unassigned |
3
1
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
18096894 |
Premature stop codon in MMP20 causing amelogenesis imperfecta. |
causal interaction
unassigned |
1
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
19578120 |
Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice. |
causal interaction
unassigned |
3
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
19966041 |
MMP20 hemopexin domain mutation in amelogenesis imperfecta. |
unassigned |
0 |
| 3.4.21.B12 | Breast Neoplasms |
18687310 |
Specific increase of human kallikrein 4 mRNA and protein levels in breast cancer stromal cells. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 3.4.21.B12 | Carcinogenesis |
22148895 |
Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs). |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
2
0 |
| 3.4.21.B12 | Carcinogenesis |
31829025 |
MiR-378a-5p inhibits angiogenesis of oral squamous cell carcinoma by targeting KLK4. |
causal interaction
unassigned |
4
0 |
