EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.21.118 | Adenocarcinoma |
14749636 |
The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 4 |
3.4.21.118 | Adenocarcinoma |
15138549 |
Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer. |
causal interaction diagnostic usage ongoing research unassigned |
4 4 4 0 |
3.4.21.118 | Adenocarcinoma |
20473923 |
KLK15 is a prognostic marker for progression-free survival in patients with radical prostatectomy. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 4 |
3.4.21.118 | Adenocarcinoma |
23201139 |
Kallikrein-related peptidase 4 (KLK4) mRNA predicts short-term relapse in colorectal adenocarcinoma patients. |
causal interaction diagnostic usage therapeutic application unassigned |
2 3 1 0 |
3.4.21.118 | Alzheimer Disease |
16800733 |
Activation and enzymatic characterization of recombinant human kallikrein 8. |
causal interaction diagnostic usage unassigned |
1 1 0 |
3.4.21.118 | Alzheimer Disease |
29505099 |
HIGHER LEVELS OF KALLIKREIN-8 IN FEMALE BRAIN MAY INCREASE THE RISK FOR ALZHEIMER'S DISEASE. |
causal interaction diagnostic usage unassigned |
4 2 0 |
3.4.21.118 | Alzheimer Disease |
30989572 |
Visualizing protein-ligand binding with chemical energy-wise decomposition (CHEWD): application to ligand binding in the kallikrein-8 S1 Site. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.4.21.118 | Alzheimer Disease |
31371645 |
CSF and blood Kallikrein-8: a promising early biomarker for Alzheimer's disease. |
causal interaction therapeutic application unassigned |
3 4 0 |
3.4.21.118 | Alzheimer Disease |
31734318 |
Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model. |
causal interaction ongoing research therapeutic application unassigned |
2 2 2 0 |
3.4.21.118 | Alzheimer Disease |
33341972 |
Genetic knockdown of Klk8 has sex-specific multi-targeted therapeutic effects on Alzheimer's pathology in mice. |
causal interaction therapeutic application unassigned |
4 1 0 |