EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.3.2.6 | Aberrant Crypt Foci |
14690793 |
Effects of green tea and high-fat diet on arachidonic acid metabolism and aberrant crypt foci formation in an azoxymethane-induced colon carcinogenesis mouse model. |
causal interaction
unassigned |
3
0 |
| 3.3.2.6 | Acne Vulgaris |
33592148 |
Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.3.2.6 | Acute Coronary Syndrome |
19578513 |
Biomarkers and Bioassays for Cardiovascular Diseases: Present and Future. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
1
1
0 |
| 3.3.2.6 | Acute Lung Injury |
15805137 |
Nuclear localization of leukotriene A4 hydrolase in type II alveolar epithelial cells in normal and fibrotic lung. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 3.3.2.6 | Acute Lung Injury |
27126280 |
Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H. |
therapeutic application
unassigned |
1
0 |
| 3.3.2.6 | Acute Lung Injury |
28218840 |
Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.3.2.6 | Acute Lung Injury |
32679453 |
Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 3.3.2.6 | Adenocarcinoma |
12865451 |
Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
4
0 |
| 3.3.2.6 | Adenocarcinoma |
15134534 |
Leukotriene A4 hydrolase as a target for cancer prevention and therapy. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
| 3.3.2.6 | Anthrax |
8973585 |
The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
3
1
0 |
