EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.2.1.143 | Adenocarcinoma |
33257507 |
Combined Targeting of PARG and Wee1 Causes Decreased Cell Survival and DNA Damage in an S-Phase-Dependent Manner. |
ongoing research
therapeutic application
unassigned |
3
3
0 |
| 3.2.1.143 | Adenomatous Polyps |
6406058 |
Aberration of poly(adenosine diphosphate-ribose) metabolism in human colon adenomatous polyps and cancers. |
causal interaction
diagnostic usage
unassigned |
3
3
0 |
| 3.2.1.143 | Ataxia |
30100084 |
Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. |
therapeutic application
unassigned |
1
0 |
| 3.2.1.143 | Ataxia |
30388405 |
Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. |
therapeutic application
unassigned |
1
0 |
| 3.2.1.143 | Ataxia |
30401461 |
Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
1
0 |
| 3.2.1.143 | Ataxia |
32521964 |
[Pediatric stress-induced epileptic ataxia syndrome caused by ADPRHL2 gene variation]. |
unassigned |
0 |
| 3.2.1.143 | Ataxia |
33528672 |
Episodic psychosis, ataxia, motor neuropathy with pyramidal signs (PAMP syndrome) caused by a novel mutation in ADPRHL2 (AHR3). |
causal interaction
ongoing research
unassigned |
4
2
0 |
| 3.2.1.143 | Breast Neoplasms |
19812418 |
Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells. |
ongoing research
unassigned |
3
0 |
| 3.2.1.143 | Breast Neoplasms |
22839996 |
Silencing of Apoptosis-Inducing factor and poly(ADP-ribose) glycohydrolase reveals novel roles in breast cancer cell death after chemotherapy. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
2
0 |
| 3.2.1.143 | Breast Neoplasms |
23736962 |
Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
4
2
0 |
