EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
18268335 |
Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity. |
causal interaction
unassigned |
4
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
21209202 |
Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling. |
unassigned |
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
22487514 |
A new model of Pde4d deficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects. |
causal interaction
ongoing research
unassigned |
2
1
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
24101672 |
Genetic Deletion and Pharmacological Inhibition of PDE10A Protects Mice from Diet-Induced Obesity and Insulin Resistance. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
25608528 |
Role of cAMP-Phosphodiesterase 1C Signaling in Regulating Growth Factor Receptor Stability, Vascular Smooth Muscle Cell Growth, Migration, and Neointimal Hyperplasia. |
causal interaction
unassigned |
3
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
27791092 |
PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
30307157 |
Hypothalamic PDE3B deficiency alters body weight and glucose homeostasis in mouse |
causal interaction
ongoing research
unassigned |
2
2
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
31801360 |
A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase deficiency |
34312235 |
Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.1.4.17 | Abortion, Habitual |
23237535 |
Phosphodiesterase 8B gene polymorphism in women with recurrent miscarriage: a retrospective case control study. |
ongoing research
unassigned |
4
0 |
