EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.21.10 | Adenocarcinoma |
29739952 |
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma. |
diagnostic usage
therapeutic application
unassigned |
2
3
0 |
| 3.1.21.10 | Adenocarcinoma |
30151275 |
Exceptional response to FOLFIRINOX in a patient with pancreatic cancer and a germline RAD51C mutation. |
causal interaction
therapeutic application
unassigned |
4
2
0 |
| 3.1.21.10 | Anemia |
24049073 |
Intracellular dynamics of archaeal FANCM homologue Hef in response to halted DNA replication. |
unassigned |
0 |
| 3.1.21.10 | Astrocytoma |
17034947 |
Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array. |
causal interaction
diagnostic usage
unassigned |
2
2
0 |
| 3.1.21.10 | Ataxia |
27296891 |
Rad51C-ATXN7 fusion gene expression in colorectal tumors. |
ongoing research
unassigned |
1
0 |
| 3.1.21.10 | Ataxia Telangiectasia |
18054789 |
Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.21.10 | Ataxia Telangiectasia |
19451272 |
RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation. |
therapeutic application
unassigned |
1
0 |
| 3.1.21.10 | Bloom Syndrome |
11073977 |
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. |
causal interaction
unassigned |
3
0 |
| 3.1.21.10 | Bloom Syndrome |
15143192 |
Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.1.21.10 | Bloom Syndrome |
16181657 |
Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans. |
causal interaction
unassigned |
2
0 |
