EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    3.1.2.6 | Adenocarcinoma |
16803681 |
Overexpression of glyoxalase system enzymes in human kidney tumor. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
1
4
0 |
| 3.1.2.6 | Breast Neoplasms |
11368412 |
Expression of glyoxalase I and II in normal and breast cancer tissues. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 3.1.2.6 | Breast Neoplasms |
16319983 |
A possible regulatory role of 17beta-estradiol and tamoxifen on glyoxalase I and glyoxalase II genes expression in MCF7 and BT20 human breast cancer cells. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 3.1.2.6 | Carcinogenesis |
8903102 |
Changes in concentrations of methylglyoxal, D-lactate and glyoxalase activities in liver and plasma of rats fed a 3'-methyl-4-dimethylaminoazobenzene-rich diet. |
ongoing research
unassigned |
4
0 |
| 3.1.2.6 | Carcinogenesis |
28470764 |
Glyoxalase 2 drives tumorigenesis in human prostate cells in a mechanism involving androgen receptor and p53-p21 axis. |
causal interaction
ongoing research
unassigned |
4
3
0 |
| 3.1.2.6 | Carcinoma |
12204678 |
Differing expression of enzymes of the glyoxalase system in superficial and invasive bladder carcinomas. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 3.1.2.6 | Carcinoma, Ovarian Epithelial |
18805576 |
Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
4
2
0 |
| 3.1.2.6 | Carcinoma, Renal Cell |
16803681 |
Overexpression of glyoxalase system enzymes in human kidney tumor. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
1
4
0 |
| 3.1.2.6 | Diabetes Complications |
8636255 |
Increased levels of methylglyoxal-metabolizing enzymes in mononuclear and polymorphonuclear cells from insulin-dependent diabetic patients with diabetic complications: aldose reductase, glyoxalase I, and glyoxalase II--a clinical research center study. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
1
3
0 |
| 3.1.2.6 | Diabetes Complications |
22893478 |
Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus. |
ongoing research
unassigned |
4
0 |
