EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.11.2 | Acquired Immunodeficiency Syndrome |
12367650 |
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
1
0 |
| 3.1.11.2 | Adenocarcinoma |
28943952 |
miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma. |
causal interaction
unassigned |
4
0 |
| 3.1.11.2 | African Swine Fever |
8623526 |
Evolutionary relationships among large double-stranded DNA viruses that infect microalgae and other organisms as inferred from DNA polymerase genes. |
ongoing research
unassigned |
2
0 |
| 3.1.11.2 | Alzheimer Disease |
34528746 |
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease. |
causal interaction
unassigned |
4
0 |
| 3.1.11.2 | Blindness |
22869729 |
ERK1/2 activation is a therapeutic target in age-related macular degeneration. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.1.11.2 | Bloom Syndrome |
28279982 |
A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
3
0 |
| 3.1.11.2 | Brain Neoplasms |
20551246 |
Genomic analysis of the 55 kDa subunit of DNA polymerase epsilon in human intracranial neoplasms. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
4
0 |
| 3.1.11.2 | Breast Neoplasms |
12713808 |
The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 3.1.11.2 | Breast Neoplasms |
19129559 |
Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
4
0 |
| 3.1.11.2 | Carcinogenesis |
8819107 |
Potential role of DNA polymerase beta in gene therapy against cancer: a case for colorectal cancer. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
4
0 |
