EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.1.1.106 | Breast Neoplasms |
25422431 |
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 2 1 |
3.1.1.106 | Carcinogenesis |
29880585 |
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 1 |
3.1.1.106 | Carcinogenesis |
30619475 |
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. |
causal interaction ongoing research therapeutic application unassigned |
3 2 1 0 |
3.1.1.106 | Carcinogenesis |
31921812 |
Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes. |
causal interaction diagnostic usage therapeutic application unassigned |
2 3 1 0 |
3.1.1.106 | Carcinogenesis |
32151005 |
The Controversial Roles of ADP-Ribosyl Hydrolases MACROD1, MACROD2 and TARG1 in Carcinogenesis. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.1.1.106 | Carcinoma, Hepatocellular |
32257385 |
MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3?/?-catenin signaling. |
causal interaction diagnostic usage ongoing research unassigned |
4 4 1 0 |
3.1.1.106 | Colonic Neoplasms |
30034629 |
MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 4 4 3 |
3.1.1.106 | Colorectal Neoplasms |
29880585 |
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 1 |
3.1.1.106 | Colorectal Neoplasms |
30237848 |
MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer. |
causal interaction diagnostic usage unassigned |
1 1 0 |
3.1.1.106 | Colorectal Neoplasms |
31921812 |
Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes. |
causal interaction diagnostic usage therapeutic application unassigned |
2 3 1 0 |