EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.8.2.30 | Angioedemas, Hereditary |
33508266 |
Novel hereditary angioedema linked with a heparan sulfate 3-O-sulfotransferase 6 gene mutation. |
causal interaction
therapeutic application
unassigned |
2
2
0 |
| 2.8.2.30 | Breast Neoplasms |
27041583 |
The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 2.8.2.30 | Breast Neoplasms |
28017727 |
Silencing HS6ST3 inhibits growth and progression of breast cancer cells through suppressing IGF1R and inducing XAF1. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
4 |
| 2.8.2.30 | Breast Neoplasms |
29547633 |
The heparan sulfate 3-O-sulfotransferases (HS3ST) 2, 3B and 4 enhance proliferation and survival in breast cancer MDA-MB-231 cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
2
0 |
| 2.8.2.30 | Breast Neoplasms |
30360368 |
The Pro-Tumoral Activity of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) in Breast Cancer MDA-MB-231 Cells Is Dependent on the Expression of Neuropilin-1. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 2.8.2.30 | Carcinogenesis |
28017727 |
Silencing HS6ST3 inhibits growth and progression of breast cancer cells through suppressing IGF1R and inducing XAF1. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
4 |
| 2.8.2.30 | Carcinoma, Hepatocellular |
16534869 |
P120ctn overexpression enhances beta-catenin-E-cadherin binding and down regulates expression of survivin and cyclin D1 in BEL-7404 hepatoma cells. |
ongoing research
unassigned |
4
0 |
| 2.8.2.30 | Carcinoma, Non-Small-Cell Lung |
29516954 |
Heparan sulfate D-glucosamine 3-O-sulfotransferase 3B1 is a novel regulator of transforming growth factor-beta-mediated epithelial-to-mesenchymal transition and regulated by miR-218 in nonsmall cell lung cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
4
0 |
| 2.8.2.30 | Chondrosarcoma |
19812376 |
Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 2.8.2.30 | Chondrosarcoma |
22903264 |
Cartilage tumour progression is characterized by an increased expression of heparan sulphate 6O-sulphation-modifying enzymes. |
diagnostic usage
unassigned |
3
0 |
