EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.7.65 | Enteritis |
28888651 |
Necrotic enteritis locus 1 diguanylate cyclase and phosphodiesterase (cyclic-di-GMP) gene mutation attenuates virulence in an avian necrotic enteritis isolate of Clostridium perfringens. |
causal interaction
unassigned |
2
0 |
| 2.7.7.65 | Infections |
18978058 |
The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic Di-GMP in host cell infection. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
3
0 |
| 2.7.7.65 | Infections |
23782800 |
Transcriptome profiling analysis of Vibrio vulnificus during human infection. |
ongoing research
unassigned |
2
0 |
| 2.7.7.65 | Infections |
24846383 |
Chp8, a diguanylate cyclase from Pseudomonas syringae pv. Tomato DC3000, suppresses the pathogen-associated molecular pattern flagellin, increases extracellular polysaccharides, and promotes plant immune evasion. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 2.7.7.65 | Infections |
26940526 |
Membrane association of SadC enhances its diguanylate cyclase activity to control exopolysaccharides synthesis and biofilm formation in Pseudomonas aeruginosa. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 2.7.7.65 | Infections |
27537839 |
Evaluation of a Salmonella Strain Lacking the Secondary Messenger C-di-GMP and RpoS as a Live Oral Vaccine. |
causal interaction
unassigned |
1
0 |
| 2.7.7.65 | Infections |
31209073 |
Bordetella bronchiseptica Diguanylate Cyclase BdcA Regulates Motility and Is Important for the Establishment of Respiratory Infection in Mice. |
causal interaction
unassigned |
3
0 |
| 2.7.7.65 | Infections |
32636243 |
The Nitrite Transporter Facilitates Biofilm Formation via Suppression of Nitrite Reductase and Is a New Antibiofilm Target in Pseudomonas aeruginosa. |
unassigned |
0 |
| 2.7.7.65 | Lyme Disease |
21542866 |
The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes. |
unassigned |
0 |
| 2.7.7.65 | Tuberculosis |
27450520 |
Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c. |
unassigned |
0 |
