EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.7.4.9 | Acquired Immunodeficiency Syndrome |
9521686 |
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. |
causal interaction
unassigned |
4
0 |
| 2.7.4.9 | Anthrax |
18260009 |
Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
| 2.7.4.9 | Ataxia Telangiectasia |
30199284 |
Thymidylate kinase is critical for DNA repair via ATM-dependent Tip60 complex formation. |
therapeutic application
unassigned |
1
0 |
| 2.7.4.9 | Carcinoma, Hepatocellular |
556350 |
Metabolism of 5-fluorouracil in sensitive and resistant tumor cells. |
diagnostic usage
ongoing research
unassigned |
3
3
0 |
| 2.7.4.9 | Carcinoma, Hepatocellular |
2561052 |
Growth inhibition of Kirkman-Robbins hepatoma by 1-(1,3-dihydroxy-2-propoxymethyl)-5,6-tetramethyleneuracil and possible mechanism of its biological activity. |
unassigned |
0 |
| 2.7.4.9 | Carcinoma, Hepatocellular |
4323166 |
Purification and properties of thymidine monophosphate kinase from mouse hepatoma. |
ongoing research
unassigned |
4
0 |
| 2.7.4.9 | Colonic Neoplasms |
18413751 |
Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
3
4
0 |
| 2.7.4.9 | Colonic Neoplasms |
23394555 |
Thymidylate kinase: an old topic brings new perspectives. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 2.7.4.9 | Embryo Loss |
823112 |
Enzymatic activities leading to pyrimidine nucleotide biosynthesis from cell-free extracts of Rickettsia typhi. |
causal interaction
diagnostic usage
unassigned |
1
3
0 |
| 2.7.4.9 | Herpes Simplex |
3037945 |
An optimized thymidylate kinase assay, based on enzymatically synthesized 5-[125I]iododeoxyuridine monophosphate and its application to an immunological study of herpes simplex virus thymidine-thymidylate kinases. |
ongoing research
unassigned |
4
0 |
