EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.11.2 | Acidosis |
2095718 |
Dichloroacetate attenuates myocardial acidosis and metabolic changes induced by partial occlusion of the coronary artery in dogs. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
1
2
0 |
| 2.7.11.2 | Acidosis, Lactic |
25212175 |
Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.7.11.2 | Acidosis, Lactic |
27486821 |
Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.7.11.2 | Acidosis, Lactic |
28163135 |
A Mechanism-Based Pharmacokinetic Enzyme Turnover Model for Dichloroacetic Acid Autoinhibition in Rats. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.7.11.2 | Acute Kidney Injury |
28040265 |
Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
3
1 |
| 2.7.11.2 | Adenocarcinoma |
28611197 |
Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. |
therapeutic application
unassigned |
4
0 |
| 2.7.11.2 | Adenocarcinoma |
31724279 |
p,p'-Dichlorodiphenyltrichloroethane promotes aerobic glycolysis via reactive oxygen species-mediated extracellular signal-regulated kinase/M2 isoform of pyruvate kinase (PKM2) signaling in colorectal cancer cells. |
causal interaction
unassigned |
4
0 |
| 2.7.11.2 | Adenocarcinoma of Lung |
30457021 |
PDK2 induces Cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
3
0 |
| 2.7.11.2 | Adenoma |
11683718 |
Isolation of expressed sequence tags of skeletal muscle of neonatal healthy and splay leg piglets and mapping by somatic cell hybrid analysis. |
ongoing research
unassigned |
1
0 |
| 2.7.11.2 | Arrhythmogenic Right Ventricular Dysplasia |
34147413 |
A review of the underlying genetics and emerging therapies for canine cardiomyopathies. |
causal interaction
unassigned |
2
0 |
