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Results 1 - 10 of 138 > >>
EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Acute Lung Injury 11714830 Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. causal interaction
unassigned
3
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Arthritis, Rheumatoid 24244039 Novel phosphoinositide 3-kinase ?,? inhibitor: potent anti-inflammatory effects and joint protection in models of rheumatoid arthritis. causal interaction
ongoing research
therapeutic application
unassigned
2
3
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Arthritis, Rheumatoid 24262886 Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-yl}acetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase ? inhibitor for the treatment of inflammatory diseases. causal interaction
therapeutic application
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Asthma 20148286 Consensus model for identification of novel PI3K inhibitors in large chemical library. causal interaction
therapeutic application
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Asthma 20351038 Phosphoinositide 3-kinase {delta} inhibitor suppresses IL-17 expression in a murine asthma model. causal interaction
ongoing research
therapeutic application
unassigned
4
1
3
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Asthma 27556731 Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002. causal interaction
ongoing research
therapeutic application
unassigned
1
4
1
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Asthma 29651336 PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge. causal interaction
diagnostic usage
ongoing research
therapeutic application
2
3
4
2
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Autoimmune Diseases 16789742 Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma. causal interaction
therapeutic application
unassigned
2
3
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Autoimmune Diseases 19689378 Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma. causal interaction
therapeutic application
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.154Autoimmune Diseases 24735732 PI3K inhibitors as potential therapeutics for autoimmune disease. causal interaction
therapeutic application
unassigned
4
4
0
Results 1 - 10 of 138 > >>