EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.7.1.154 | Acute Lung Injury |
11714830 |
Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. |
causal interaction unassigned |
3 0 |
2.7.1.154 | Arthritis, Rheumatoid |
24244039 |
Novel phosphoinositide 3-kinase ?,? inhibitor: potent anti-inflammatory effects and joint protection in models of rheumatoid arthritis. |
causal interaction ongoing research therapeutic application unassigned |
2 3 4 0 |
2.7.1.154 | Arthritis, Rheumatoid |
24262886 |
Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-yl}acetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase ? inhibitor for the treatment of inflammatory diseases. |
causal interaction therapeutic application unassigned |
4 4 0 |
2.7.1.154 | Asthma |
20148286 |
Consensus model for identification of novel PI3K inhibitors in large chemical library. |
causal interaction therapeutic application unassigned |
4 4 0 |
2.7.1.154 | Asthma |
20351038 |
Phosphoinositide 3-kinase {delta} inhibitor suppresses IL-17 expression in a murine asthma model. |
causal interaction ongoing research therapeutic application unassigned |
4 1 3 0 |
2.7.1.154 | Asthma |
27556731 |
Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002. |
causal interaction ongoing research therapeutic application unassigned |
1 4 1 0 |
2.7.1.154 | Asthma |
29651336 |
PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 3 4 2 |
2.7.1.154 | Autoimmune Diseases |
16789742 |
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma. |
causal interaction therapeutic application unassigned |
2 3 0 |
2.7.1.154 | Autoimmune Diseases |
19689378 |
Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma. |
causal interaction therapeutic application unassigned |
4 4 0 |
2.7.1.154 | Autoimmune Diseases |
24735732 |
PI3K inhibitors as potential therapeutics for autoimmune disease. |
causal interaction therapeutic application unassigned |
4 4 0 |