EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.4.1.228 | (n-acetylneuraminyl)-galactosylglucosylceramide n-acetylgalactosaminyltransferase deficiency |
10731680 |
Essential roles of carbohydrate signals in development, immune response and tissue functions, as revealed by gene targeting. |
causal interaction
unassigned |
4
0 |
| 2.4.1.228 | Abortion, Spontaneous |
32667820 |
Two Thai Burmese descendants with A4GALT*01N.21, p phenotype, and anti-PP1Pk. |
ongoing research
unassigned |
1
0 |
| 2.4.1.228 | Acute Kidney Injury |
28490444 |
Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. |
causal interaction
unassigned |
2
0 |
| 2.4.1.228 | Acute Kidney Injury |
31331463 |
Lose the lipid: renoprotection conferred by Gb3 synthase knockout. |
therapeutic application
unassigned |
1
0 |
| 2.4.1.228 | Adenocarcinoma of Lung |
24735752 |
Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.4.1.228 | Adenocarcinoma of Lung |
26001295 |
An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
4
1
0 |
| 2.4.1.228 | Alzheimer Disease |
24977484 |
PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease. |
causal interaction
unassigned |
4
0 |
| 2.4.1.228 | Amyotrophic Lateral Sclerosis |
26483191 |
Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase. |
unassigned |
0 |
| 2.4.1.228 | Bone Diseases |
17919546 |
Effect of miglustat on bone disease in adults with type 1 Gaucher disease: a pooled analysis of three multinational, open-label studies. |
causal interaction
therapeutic application
unassigned |
1
3
0 |
| 2.4.1.228 | Brain Ischemia |
15181369 |
Glucosylceramide synthase activity and ceramide levels are modulated during cerebral ischemia after ischemic preconditioning. |
causal interaction
unassigned |
2
0 |
