EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.3.1.B43 | Acute Coronary Syndrome |
32931562 |
Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 2.3.1.B43 | Acute Kidney Injury |
31815138 |
Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.3.1.B43 | Adenocarcinoma |
34245764 |
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
2
2 |
| 2.3.1.B43 | Alzheimer Disease |
27858336 |
Sirtuin 5: a review of structure, known inhibitors and clues for developing new inhibitors. |
causal interaction
unassigned |
4
0 |
| 2.3.1.B43 | Alzheimer Disease |
33098511 |
Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
4
0 |
| 2.3.1.B43 | Arthritis |
32099074 |
Sirtuin 5 deficiency increases disease severity in rats with adjuvant-induced arthritis. |
causal interaction
unassigned |
4
0 |
| 2.3.1.B43 | Bacterial Infections |
30515162 |
Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections. |
therapeutic application
unassigned |
4
0 |
| 2.3.1.B43 | Bacterial Infections |
32415480 |
SIRT5 is important for bacterial infection by regulating insulin secretion and glucose homeostasis. |
causal interaction
unassigned |
3
0 |
| 2.3.1.B43 | Brain Injuries |
29622432 |
Sirtuin 5 as a novel target to blunt blood-brain barrier damage induced by cerebral ischemia/reperfusion injury. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.3.1.B43 | Brain Ischemia |
27435822 |
Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5. |
unassigned |
0 |
