EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.1.2.3 | Adenocarcinoma |
31707355 |
Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.1.2.3 | Arthritis |
21515602 |
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis. |
causal interaction
unassigned |
2
0 |
| 2.1.2.3 | Arthritis |
25240429 |
5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 2.1.2.3 | Arthritis, Juvenile |
21515602 |
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis. |
causal interaction
unassigned |
2
0 |
| 2.1.2.3 | Arthritis, Juvenile |
25240429 |
5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 2.1.2.3 | Arthritis, Rheumatoid |
10855951 |
Effects of methotrexate on nucleotide pools in normal human T cells and the CEM T cell line. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.1.2.3 | Arthritis, Rheumatoid |
19174154 |
Metabolism-blocked antifolates as potential anti-rheumatoid arthritis agents: 4-amino-4-deoxy-5,8,10-trideazapteroyl-d,l-4'-methyleneglutamic acid (CH-1504) and its analogs. |
unassigned |
0 |
| 2.1.2.3 | Arthritis, Rheumatoid |
20404044 |
Evidence for the hypothesis that 10-formyldihydrofolate is the in vivo substrate for aminoimidazolecarboxamide ribotide transformylase. |
causal interaction
unassigned |
3
0 |
| 2.1.2.3 | Arthritis, Rheumatoid |
27379764 |
Association of the ATIC 347 C/G polymorphism with responsiveness to and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.1.2.3 | Ataxia Telangiectasia |
31983282 |
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
