EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.5.3.2 | Abortion, Spontaneous |
34350169 |
RNA Demethylase FTO Mediated RNA m6A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion. |
causal interaction
ongoing research
unassigned |
2
4
0 |
| 1.5.3.2 | Acute Kidney Injury |
34226503 |
DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 1.5.3.2 | Adenocarcinoma |
31906946 |
m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
2
1 |
| 1.5.3.2 | Adenocarcinoma of Lung |
27346347 |
Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells. |
unassigned |
0 |
| 1.5.3.2 | Adenocarcinoma of Lung |
30455465 |
H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 1.5.3.2 | Adenocarcinoma of Lung |
31677788 |
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
3
0 |
| 1.5.3.2 | Adenocarcinoma of Lung |
33291558 |
Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
3
1 |
| 1.5.3.2 | Alzheimer Disease |
20573497 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models. |
causal interaction
unassigned |
1
0 |
| 1.5.3.2 | Anthrax |
20360974 |
The role of NF-kappaB and H3K27me3 demethylase, Jmjd3, on the anthrax lethal toxin tolerance of RAW 264.7 cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
3
0 |
| 1.5.3.2 | Atherosclerosis |
28798687 |
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System. |
causal interaction
unassigned |
3
0 |
