EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.19.30 | Acute Coronary Syndrome |
32595194 |
Relationships of Fatty Acids, Delta-5 Desaturase Activity, and Lipid Profiles in Men with Acute Coronary Syndrome. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 1.14.19.30 | Atherosclerosis |
33600308 |
Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development. |
ongoing research
therapeutic application
unassigned |
3
4
0 |
| 1.14.19.30 | Breast Neoplasms |
29587668 |
Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-?-linolenic acid peroxidation dependent mechanism. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
3
0 |
| 1.14.19.30 | Breast Neoplasms |
32931930 |
Growth inhibitory and anti-metastatic activity of epithelial cell adhesion molecule targeted three-way junctional delta-5-desaturase siRNA nanoparticle for breast cancer therapy. |
diagnostic usage
ongoing research
unassigned |
3
3
0 |
| 1.14.19.30 | Carcinoma, Hepatocellular |
2328022 |
Linoleate and linolenate desaturation by rat hepatoma cells. |
diagnostic usage
ongoing research
unassigned |
1
1
0 |
| 1.14.19.30 | Cardiovascular Diseases |
34413950 |
Novel Heterocyclic Compounds as Delta-5-Desaturase Inhibitors for Treating Metabolic and Cardiovascular Diseases. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 1.14.19.30 | Colitis, Ulcerative |
7775867 |
Modulation in delta 9, delta 6, and delta 5 fatty acid desaturase activity in the human intestinal CaCo-2 cell line. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 1.14.19.30 | Colonic Neoplasms |
27101738 |
Knockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-?-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
1
2
4 |
| 1.14.19.30 | Colonic Neoplasms |
27368132 |
Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ?-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 1.14.19.30 | Colonic Neoplasms |
28157665 |
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
4 |
