EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.15.29 | Infections |
19846552 |
The structure of Mycobacterium tuberculosis CYP125: Molecular basis for cholesterol binding in a P450 needed for host infection. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
2
3
0 |
| 1.14.15.29 | Infections |
21109436 |
Reverse type I inhibitor of Mycobacteriumtuberculosis CYP125A1. |
therapeutic application
unassigned |
3
0 |
| 1.14.15.29 | Infections |
21426022 |
The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 1.14.15.29 | Tuberculosis |
17846131 |
Small-Molecule Scaffolds for CYP51 Inhibitors Identified by High-Throughput Screening and Defined by X-Ray Crystallography. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 1.14.15.29 | Tuberculosis |
19843222 |
Cytochrome P450 125 (CYP125) catalyzes C26-hydroxylation to initiate sterol side chain degradation in Rhodococcus jostii RHA1. |
unassigned |
0 |
| 1.14.15.29 | Tuberculosis |
19846551 |
Mycobacterial cytochrome P450 125 (Cyp125) catalyzes the terminal hydroxylation of C27-steroids. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 1.14.15.29 | Tuberculosis |
19846552 |
The structure of Mycobacterium tuberculosis CYP125: Molecular basis for cholesterol binding in a P450 needed for host infection. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
2
3
0 |
| 1.14.15.29 | Tuberculosis |
20545858 |
Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one. |
unassigned |
0 |
| 1.14.15.29 | Tuberculosis |
20843794 |
Functional redundancy of steroid C26-monooxygenase activity in mycobacterium tuberculosis revealed by biochemical and genetic analyses. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
2
2
1
0 |
| 1.14.15.29 | Tuberculosis |
21109436 |
Reverse type I inhibitor of Mycobacteriumtuberculosis CYP125A1. |
therapeutic application
unassigned |
3
0 |
