EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.14.11.68 | Acrocephalosyndactylia |
33298158 |
Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome. |
causal interaction therapeutic application unassigned |
3 4 0 |
1.14.11.68 | Adenocarcinoma |
30306561 |
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas. |
causal interaction therapeutic application unassigned |
4 4 0 |
1.14.11.68 | Adenocarcinoma |
30556125 |
Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 1 2 |
1.14.11.68 | Adenocarcinoma |
32154941 |
HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer. |
causal interaction unassigned |
4 0 |
1.14.11.68 | Adenocarcinoma |
32236961 |
Blocking the road to de-differentiation: HNF1A/KDM6A complex safeguards epithelial integrity in pancreatic cancer. |
unassigned |
0 |
1.14.11.68 | Adenocarcinoma |
32765772 |
KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-?/SMAD signaling pathway. |
causal interaction therapeutic application unassigned |
4 1 0 |
1.14.11.68 | Alagille Syndrome |
31414320 |
Cystic biliary atresia with paucity of bile ducts and gene mutation in KDM6A: a case report. |
causal interaction diagnostic usage therapeutic application unassigned |
4 4 1 0 |
1.14.11.68 | Amyloidosis |
33262528 |
A highly heterogeneous mutational pattern in POEMS syndrome. |
unassigned |
0 |
1.14.11.68 | Apnea |
33301470 |
A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction. |
causal interaction diagnostic usage unassigned |
4 3 0 |
1.14.11.68 | Arthritis |
33540246 |
LncRNA H19 regulates macrophage polarization and promotes Freund's complete adjuvant-induced arthritis by upregulating KDM6A. |
ongoing research therapeutic application unassigned |
2 1 0 |