EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.13.11.24 | Breast Neoplasms |
23374458 |
High levels of ?-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
| 1.13.11.24 | Breast Neoplasms |
34262943 |
Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study. |
therapeutic application
unassigned |
1
0 |
| 1.13.11.24 | Carcinogenesis |
33557375 |
Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 1.13.11.24 | Carcinoma |
31436299 |
Curcumin decreases epithelial?mesenchymal transition by a Pirin?dependent mechanism in cervical cancer cells. |
ongoing research
therapeutic application
unassigned |
2
4
0 |
| 1.13.11.24 | Infections |
18067462 |
Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 1.13.11.24 | Lymphoma, B-Cell |
14573596 |
Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. |
causal interaction
unassigned |
1
0 |
| 1.13.11.24 | Melanoma |
20089166 |
Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches. |
causal interaction
unassigned |
1
0 |
| 1.13.11.24 | Melanoma |
20711196 |
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
4
0 |
| 1.13.11.24 | Neoplasm Metastasis |
14969819 |
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 1.13.11.24 | Neoplasm Metastasis |
25680527 |
Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
