EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.170 | 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) deficiency |
17028112 |
Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development. |
causal interaction
unassigned |
4
0 |
| 1.1.1.170 | Abscess |
31502355 |
Tympanoxyloid verruciform xanthoma is a distinct feature of CHILD nevus. |
causal interaction
unassigned |
1
0 |
| 1.1.1.170 | Brain Diseases |
33775046 |
[Genotype and phenotype analysis of neonates with neonatal encephalopathy complicated with perinatal hypoxic event]. |
causal interaction
unassigned |
1
0 |
| 1.1.1.170 | Breast Neoplasms |
32366230 |
NAD(P)-dependent steroid dehydrogenase-like is involved in breast cancer cell growth and metastasis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
4 |
| 1.1.1.170 | Breast Neoplasms |
33864166 |
NSDHL promotes triple-negative breast cancer metastasis through the TGF? signaling pathway and cholesterol biosynthesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
4
4 |
| 1.1.1.170 | Carcinoma |
26344763 |
Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
4
0 |
| 1.1.1.170 | Carcinoma |
32976774 |
Cholesterol Pathway Inhibition Induces TGF-? Signaling to Promote Basal Differentiation in Pancreatic Cancer. |
therapeutic application
unassigned |
1
0 |
| 1.1.1.170 | Carcinoma |
34513998 |
A New Survival Model Based on Cholesterol Biosynthesis-Related Genes for Prognostic Prediction in Clear Cell Renal Cell Carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
3
1 |
| 1.1.1.170 | Dermatitis, Exfoliative |
22113624 |
Expression profile of NSDHL in human peripheral tissues. |
causal interaction
unassigned |
1
0 |
| 1.1.1.170 | Dermatitis, Exfoliative |
33139364 |
Novel NSDHL gene variant for congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) syndrome. |
unassigned |
0 |
