EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   3.6.5.6 | Leukemia |
23756174 |
(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells. |
ongoing research
therapeutic application
unassigned |
3
4
0 |
| 3.6.5.6 | Neoplasms |
23756174 |
(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells. |
ongoing research
therapeutic application
unassigned |
3
4
0 |
| 3.6.5.6 | Neoplasms |
30197030 |
(E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 3.6.5.6 | Prostatic Neoplasms |
18367102 |
(Z)-1,1-Dichloro-2-(4-methoxyphenyl)-3-phenylcyclopropane induces concentration-dependent growth inhibition, apoptosis, and coordinates regulation of apoptotic genes in TRAMP cells. |
ongoing research
unassigned |
1
0 |
| 3.6.5.6 | Carcinoma, Hepatocellular |
26343141 |
1,3,4-oxadiazole-2-thione Derivatives; Novel Approach for Anticancer and Tubulin Polymerization Inhibitory Activities. |
therapeutic application
unassigned |
4
0 |
| 3.6.5.6 | Breast Neoplasms |
34159741 |
1,3-Benzodioxole-Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure. |
therapeutic application
unassigned |
1
0 |
| 3.6.5.6 | Neoplasms |
30476825 |
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase. |
unassigned |
0 |
| 3.6.5.6 | Neuroblastoma |
20067570 |
1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination. |
diagnostic usage
ongoing research
unassigned |
4
2
0 |
| 3.6.5.6 | Colonic Neoplasms |
31174062 |
1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy. |
unassigned |
0 |
| 3.6.5.6 | Neoplasms |
19220018 |
10-(2-oxo-2-Phenylethylidene)-10H-anthracen-9-ones as Highly Active Antimicrotubule Agents: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
