EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.1.11.2 | Acquired Immunodeficiency Syndrome |
12367650 |
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient. |
causal interaction ongoing research therapeutic application unassigned |
1 1 1 0 |
3.1.11.2 | Adenocarcinoma |
28943952 |
miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma. |
causal interaction unassigned |
4 0 |
3.1.11.2 | African Swine Fever |
8623526 |
Evolutionary relationships among large double-stranded DNA viruses that infect microalgae and other organisms as inferred from DNA polymerase genes. |
ongoing research unassigned |
2 0 |
3.1.11.2 | Alzheimer Disease |
34528746 |
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease. |
causal interaction unassigned |
4 0 |
3.1.11.2 | Blindness |
22869729 |
ERK1/2 activation is a therapeutic target in age-related macular degeneration. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.1.11.2 | Bloom Syndrome |
28279982 |
A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. |
causal interaction ongoing research therapeutic application unassigned |
3 3 3 0 |
3.1.11.2 | Breast Neoplasms |
12713808 |
The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress. |
causal interaction ongoing research unassigned |
1 3 0 |
3.1.11.2 | Breast Neoplasms |
19129559 |
Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer. |
causal interaction diagnostic usage ongoing research unassigned |
4 2 4 0 |
3.1.11.2 | Carcinogenesis |
8819107 |
Potential role of DNA polymerase beta in gene therapy against cancer: a case for colorectal cancer. |
causal interaction diagnostic usage therapeutic application unassigned |
4 4 4 0 |
3.1.11.2 | Carcinogenesis |
11133819 |
Candidate mutator genes in mismatch repair-deficient thymic lymphomas: no evidence of mutations in the DNA polymerase delta gene. |
causal interaction diagnostic usage ongoing research unassigned |
3 1 2 0 |