EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.5.1.21 | Acidosis |
9503410 |
[Inhibitory action of natural compounds of microbial origin on cholesterol metabolism] |
therapeutic application unassigned |
1 0 |
2.5.1.21 | Acquired Immunodeficiency Syndrome |
10669567 |
Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads. |
causal interaction therapeutic application unassigned |
2 4 0 |
2.5.1.21 | Acute Lung Injury |
22949548 |
Streptococcal M1 protein triggers farnesyltransferase-dependent formation of CXC chemokines in alveolar macrophages and neutrophil infiltration in the lung. |
causal interaction ongoing research therapeutic application unassigned |
4 3 4 0 |
2.5.1.21 | Adenocarcinoma |
9770500 |
A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma. |
causal interaction ongoing research therapeutic application unassigned |
4 2 1 0 |
2.5.1.21 | Adenocarcinoma |
12663718 |
Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 3 2 4 |
2.5.1.21 | Adenocarcinoma |
17348444 |
Expression of PTEN and FHIT is involved in regulating the balance between apoptosis and proliferation in lung carcinomas. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 4 4 1 |
2.5.1.21 | Adenocarcinoma |
22272079 |
Enhanced Antiproliferative and Apoptotic Response of HT-29 Adenocarcinoma Cells to Combination of Photoactivated Hypericin and Farnesyltransferase Inhibitor Manumycin A. |
ongoing research therapeutic application unassigned |
2 3 0 |
2.5.1.21 | Adenocarcinoma |
31677963 |
The diagnostic utility of zinc E-box 1 (ZEB1) transcription factor for identification of pulmonary sarcomatoid carcinoma in cytologic and surgical specimens. |
diagnostic usage therapeutic application unassigned |
3 2 0 |
2.5.1.21 | Adenoma |
10607742 |
Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. |
causal interaction ongoing research therapeutic application unassigned |
4 4 4 0 |
2.5.1.21 | Adenoma |
33307558 |
Role of the Mevalonate Pathway in Adrenocortical Tumorigenesis. |
causal interaction ongoing research unassigned |
3 1 0 |