EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   2.3.2.B8 | Neoplasms |
8524278 |
Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes. |
causal interaction
unassigned |
4
0 |
| 2.3.2.B8 | Neoplasms |
9450543 |
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. |
causal interaction
diagnostic usage
unassigned |
3
1
0 |
| 2.3.2.B8 | Neoplasms |
10421634 |
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity. |
causal interaction
unassigned |
3
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
12783850 |
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. |
causal interaction
unassigned |
4
0 |
| 2.3.2.B8 | Wilms Tumor |
15254018 |
Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney. |
ongoing research
unassigned |
1
0 |
| 2.3.2.B8 | Neoplasms |
15288542 |
A HECT E3 ubiquitin-protein ligase with sequence similarity to E6AP does not target p53 for degradation in the softshell clam (Mya arenaria). |
unassigned |
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
15480834 |
Ultrastructural localization of parkin in the rat brainstem, thalamus and basal ganglia. |
unassigned |
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
16096643 |
14-3-3eta is a novel regulator of parkin ubiquitin ligase. |
causal interaction
ongoing research
unassigned |
4
2
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
16375772 |
Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.3.2.B8 | Parkinson Disease |
16714300 |
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. |
causal interaction
unassigned |
4
0 |
