EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   2.3.2.B8 | Neoplasms |
10421634 |
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity. |
causal interaction
unassigned |
3
0 |
| 2.3.2.B8 | Neoplasms |
26592964 |
Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata. |
causal interaction
unassigned |
1
0 |
| 2.3.2.B8 | Neoplasms |
28210267 |
MiR-30 Family Potentially Targeting PI3K-SIAH2 Predicted Interaction Network Represents a Novel Putative Theranostic Panel in Non-small Cell Lung Cancer. |
causal interaction
unassigned |
4
0 |
| 2.3.2.B8 | Neoplasms |
33116152 |
Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma models. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
1
4
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
12783850 |
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. |
causal interaction
unassigned |
4
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
16096643 |
14-3-3eta is a novel regulator of parkin ubiquitin ligase. |
causal interaction
ongoing research
unassigned |
4
2
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
16375772 |
Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.3.2.B8 | Parkinsonian Disorders |
16714300 |
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. |
causal interaction
unassigned |
4
0 |
| 2.3.2.B8 | Neoplasms |
9450543 |
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. |
causal interaction
diagnostic usage
unassigned |
3
1
0 |
| 2.3.2.B8 | Retinoblastoma |
29344143 |
Function of cell-cycle regulators in predicting silent pituitary adenoma progression following surgical resection. |
diagnostic usage
therapeutic application
unassigned |
2
1
0 |
