EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.14.15.3 | Uremia |
19232159 |
1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis. |
causal interaction
diagnostic usage
unassigned |
3
2
0 |
| 1.14.15.3 | Hypertension |
23584425 |
20-HETE and Blood Pressure Regulation: Clinical Implications. |
causal interaction
unassigned |
1
0 |
| 1.14.15.3 | Neoplasms |
22798501 |
20-HETE-producing enzymes are up-regulated in human cancers. |
causal interaction
unassigned |
1
0 |
| 1.14.15.3 | Hypertension |
27298316 |
20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
| 1.14.15.3 | Cardiomegaly |
19889059 |
3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 1.14.15.3 | Gliosarcoma |
16352703 |
9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A. |
unassigned |
0 |
| 1.14.15.3 | Neoplasms |
16352703 |
9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A. |
unassigned |
0 |
| 1.14.15.3 | Hypertension |
21326303 |
A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population. |
ongoing research
therapeutic application
unassigned |
4
2
0 |
| 1.14.15.3 | Essential Hypertension |
18300855 |
A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
3
4
1 |
| 1.14.15.3 | Hypertension |
18300855 |
A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
3
4
1 |
