EC Number   |
Disease  |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.1.1.105 | Adenocarcinoma of Lung |
18788756 |
Oxidation of PAH trans-Dihydrodiols by Human Aldo-Keto Reductase AKR1B10. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
| 1.1.1.105 | Adenoma |
23639973 |
Retinoid acid receptor expression is helpful to distinguish between adenoma and well-differentiated carcinoma in the thyroid. |
diagnostic usage
unassigned |
1
0 |
| 1.1.1.105 | all-trans-retinol dehydrogenase (nad+) deficiency |
23267101 |
Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males. |
causal interaction
unassigned |
1
0 |
| 1.1.1.105 | all-trans-retinol dehydrogenase (nad+) deficiency |
27740873 |
Retinol Dehydrogenase-10 Regulates Pancreas Organogenesis and Endocrine Cell Differentiation via Paracrine Retinoic Acid Signaling. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 1.1.1.105 | all-trans-retinol dehydrogenase (nad+) deficiency |
31237438 |
Development of a Gene Therapy Vector for RDH12-Associated Retinal Dystrophy. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 1.1.1.105 | Bacteremia |
33204758 |
Trends in Bacteremia Over 2 Decades in the Top End of the Northern Territory of Australia. |
causal interaction
unassigned |
2
0 |
| 1.1.1.105 | Blindness |
15865448 |
Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids. |
causal interaction
unassigned |
2
0 |
| 1.1.1.105 | Blindness |
16269441 |
Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. |
causal interaction
unassigned |
4
0 |
| 1.1.1.105 | Blindness |
17130236 |
Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function. |
causal interaction
unassigned |
3
0 |
| 1.1.1.105 | Blindness |
17197551 |
RDH12 and RPE65, visual cycle genes causing leber congenital amaurosis, differ in disease expression. |
causal interaction
unassigned |
3
0 |
