EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.1.1.105 | Retinal Dystrophies |
7028497 |
Retinal reductase activity in rats with and without inherited retinal dystrophy. |
ongoing research unassigned |
2 0 |
1.1.1.105 | Retinal Dystrophies |
15258582 |
Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy. |
causal interaction unassigned |
4 0 |
1.1.1.105 | Retinal Dystrophies |
16269441 |
Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. |
causal interaction unassigned |
4 0 |
1.1.1.105 | Retinal Dystrophies |
17011878 |
Screening genes of the retinoid metabolism: novel LRAT mutation in leber congenital amaurosis. |
ongoing research therapeutic application unassigned |
2 1 0 |
1.1.1.105 | Retinal Dystrophies |
17032653 |
Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. |
causal interaction unassigned |
3 0 |
1.1.1.105 | Retinal Dystrophies |
17130236 |
Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function. |
causal interaction unassigned |
3 0 |
1.1.1.105 | Retinal Dystrophies |
17389517 |
The phenotype of early-onset retinal degeneration in persons with RDH12 mutations. |
causal interaction diagnostic usage therapeutic application unassigned |
4 3 1 0 |
1.1.1.105 | Retinal Dystrophies |
17925390 |
Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12. |
causal interaction therapeutic application unassigned |
3 1 0 |
1.1.1.105 | Retinal Dystrophies |
18048336 |
Redundant and unique roles of retinol dehydrogenases in the mouse retina. |
causal interaction unassigned |
1 0 |
1.1.1.105 | Retinal Dystrophies |
18326732 |
Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. |
causal interaction unassigned |
3 0 |