EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
3.4.21.59 | 0.0000012 |
- |
[5-(aminomethyl)spiro[1-benzofuran-3,1'-cyclohexan]-4'-yl][5-[(2-methylphenyl)ethynyl]furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000018 |
- |
[5'-(aminomethyl)-1'-[(methylsulfinyl)oxy]-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-4-yl][5-(phenylethynyl)furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000031 |
- |
[6'-(aminomethyl)-2',3'-dihydrospiro[cyclohexane-1,1'-inden]-4-yl][5-(phenylethynyl)furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000036 |
- |
JNJ-27390467 |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000043 |
- |
[5-(aminomethyl)spiro[1-benzofuran-3,1'-cyclohexan]-4'-yl][5-[(2-fluorophenyl)ethynyl]furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000045 |
- |
[5-(aminomethyl)spiro[1-benzofuran-3,1'-cyclohexan]-4'-yl][5-(phenylethynyl)furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000051 |
- |
cyclotheonamide E4 |
- |
708126 |
3.4.21.59 | 0.0000052 |
- |
[5-(aminomethyl)spiro[1-benzofuran-3,1'-cyclohexan]-4'-yl][5-[(2-chlorophenyl)ethynyl]furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000057 |
- |
[5'-(aminomethyl)-1'-[(phenylsulfinyl)oxy]-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-4-yl][5-(phenylethynyl)furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |
3.4.21.59 | 0.0000083 |
- |
[5-(aminomethyl)spiro[1-benzofuran-3,1'-cyclohexan]-4'-yl][5-[(4-methylphenyl)ethynyl]furan-2-yl]methanone |
pH 7.4, 37°C |
683249 |