EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.2.1.143 | 0.0000026 |
- |
PDD00017273 |
pH and temperature not specified in the publication |
753397 |
| 3.2.1.143 | 0.000026 |
- |
1-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide |
pH 7.4, 22°C |
752360 |
| 3.2.1.143 | 0.00004 |
- |
1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-2,3-dihydro-1H-benzimidazole-5-sulfonamide |
pH 7.4, 22°C |
752360 |
| 3.2.1.143 | 0.0001 |
- |
adenosine diphosphate (hydroxymethyl) pyrrolidinediol |
pH 7.5, 37°C |
731453 |
| 3.2.1.143 | 0.00012 |
- |
adenosine 5'-diphosphate-(hydroxymethyl)-pyrrolidinediol |
pH and temperature not specified in the publication |
732776 |
| 3.2.1.143 | 0.00012 |
- |
ADP-(hydroxymethyl)pyrrolidinediol |
in 150 mM potassium phosphate buffer, pH 7.5, 150 mM KCl, 0.3 mg/ml bovine serum albumin, and 30 mM 2-mercaptoethanol, at 37°C |
715869 |
| 3.2.1.143 | 0.00066 |
- |
adenosine diphosphate (hydroxymethyl)pyrrolidinediol |
37°C |
707395 |
| 3.2.1.143 | 0.001 |
- |
N'1-[(E)-(2,3,4-trihydroxyphenyl)methylidene]-N'4-[(Z)-(2,3,4-trihydroxyphenyl)methylidene]benzene-1,4-dicarbohydrazide |
pH 7.5, 37°C |
731453 |
| 3.2.1.143 | 0.0011 |
- |
adenosine 5'-diphosphate (hydroxymethyl)pyrrolidinediol |
with mutant enzyme K616A/Q617A/K618A/E688A/K689A/K690A, pH 7.0, 25°C |
732714 |
| 3.2.1.143 | 0.0016 |
- |
N'1,N'3-bis[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanedihydrazide |
pH 7.5, 37°C |
731453 |
