EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.2.1.114 | 0.000005 |
- |
swainsonine |
in 50 mM sodium acetate buffer pH 5.8, at 37°C |
714909 |
| 3.2.1.114 | 0.00001 |
- |
Mannostatin A |
very potent inhibitor, competitive, IC50: about 10 nM with 4-nitrophenyl alpha-D-mannoside as substrate, about 90 nM with GlcNAc(Man)5GlcNAc as substrate, equally potent as swainsonine |
646629 |
| 3.2.1.114 | 0.00001 |
- |
swainsonine |
alpha-mannosidase III, IC50: 10 nM |
646644 |
| 3.2.1.114 | 0.00001 |
- |
swainsonine |
extracted from endothelial cells HCEC |
696732 |
| 3.2.1.114 | 0.000017 |
- |
swainsonine |
- |
682766 |
| 3.2.1.114 | 0.00002 |
- |
swainsonine |
extracted from human glioblastoma cells LNZ308 |
696732 |
| 3.2.1.114 | 0.000029 |
- |
1-(4-methylphenyl)-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone |
pH 5.75, 25°C |
708117 |
| 3.2.1.114 | 0.000029 |
- |
1-(4-tert-butylphenyl)-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone |
pH 5.75, 25°C |
708117 |
| 3.2.1.114 | 0.00003 |
- |
1-phenyl-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone |
pH 5.75, 25°C |
708117 |
| 3.2.1.114 | 0.000037 |
- |
swainsonine |
pH 5.75, 25°C |
708117 |
