EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.1.6.2 | -999 |
- |
1-[(4-cyanophenyl)(4-sulfamoyloxyphenyl)methyl]-1H-[1,2,4]triazole |
at 10 microM 21.5% inhibition of STS activity in JEG-3 cells, IC50 for aromatase = 0.000013 mM |
693555 |
| 3.1.6.2 | -999 |
- |
1-[bis-(3-sulfamoyloxy-4-methoxyphenyl)methyl]-1H-[1,2,4]triazole |
at 10 microM 10.9% inhibition of STS activity in JEG-3 cells, 40% inhibition of aromatase |
693555 |
| 3.1.6.2 | -999 |
- |
1-[bis-(3-sulfamoyloxyphenyl)methyl]-1H-[1,2,4]triazole |
at 10 microM 31.4% inhibition of STS activity in JEG-3 cells, IC50 for aromatase = 0.000099 mM |
693555 |
| 3.1.6.2 | -999 |
- |
1-[bis-(4-sulfamoyloxy-3-methoxyphenyl)methyl]-1H-[1,2,4]triazole |
at 10 microM 11.9% inhibition of STS activity in JEG-3 cells, 33% inhibition of aromatase |
693555 |
| 3.1.6.2 | 0.000000015 |
- |
6-oxo-6,7,8,9,10,11,12,13,14,15-decahydrocycloundeca[c]chromen-3-yl sulfamate |
in JEG-3 cells, pH not specified in the publication, temperature not specified in the publication |
714750 |
| 3.1.6.2 | 0.000000022 |
- |
6-oxo-6,7,8,9,10,11,12,13-octahydrocyclonona[c]chromen-3-yl sulfamate |
in JEG-3 cells, pH not specified in the publication, temperature not specified in the publication |
714750 |
| 3.1.6.2 | 0.000000025 |
- |
6-oxo-7,8,9,10,11,12,13,14-octahydro-6H-cyclodeca[c]chromen-3-yl sulfamate |
in JEG-3 cells, pH not specified in the publication, temperature not specified in the publication |
714750 |
| 3.1.6.2 | 0.000000035 |
- |
3-sulfamoyloxy-N-3,3,3-trifluoropropyl-16,17-seco-estra-1,3,4(10)-triene-16,17-imide |
in vitro JEG-3 cells: 0.001-10000 nmol/l inhibitor and incubation with estrone-3-sulfate, IC50 for human carbonic anhydrase II = 0.000003 mM |
694116 |
| 3.1.6.2 | 0.00000006 |
- |
TX-1506 |
non-steroid Theramex compound, strong inhibitor, 0.06 nM in MCF-7 cells |
656649 |
| 3.1.6.2 | 0.00000008 |
- |
estrone-3-sulfamate |
IC50 0.08 nM in MCF-7 cells |
656649 |
