EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.1.3 | 0.000007 |
- |
N8-(2-methoxyethyl)-N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.0000071 |
- |
N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.0000098 |
- |
N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)-N8-(pyridin-2-ylmethyl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.00001 |
- |
2-[4-(aminomethyl)piperidin-1-yl]-N8-(cyclopropylmethyl)-N4-[2-(methylsulfanyl)phenyl]pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.000012 |
- |
N8-cyclopropyl-N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.000016 |
- |
N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)-N8-(1,3-thiazol-2-ylmethyl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.000018 |
- |
2-[(3R)-3-aminopiperidin-1-yl]-N8-(cyclopropylmethyl)-N4-[2-(methylsulfanyl)phenyl]pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.000018 |
- |
N8-(cyclobutylmethyl)-N4-[2-(methylsulfanyl)phenyl]-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.000023 |
- |
2-[(3S)-3-aminopiperidin-1-yl]-N8-(cyclopropylmethyl)-N4-[2-(methylsulfanyl)phenyl]pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |
2.7.1.3 | 0.00003 |
- |
2-[3-(aminomethyl)azetidin-1-yl]-N8-(cyclopropylmethyl)-N4-[2-(methylsulfanyl)phenyl]pyrimido[5,4-d]pyrimidine-4,8-diamine |
pH and temperature not specified in the publication |
721134 |