EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   2.7.1.137 | 0.0000012 |
- |
SAR405 |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.000002 |
- |
(8S)-2-[(3R)-3-methylmorpholin-4-yl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.00001 |
- |
Wortmannin |
IC50 10 nM |
640944 |
| 2.7.1.137 | 0.00001 |
- |
Wortmannin |
IC50: 10 nM |
640917 |
| 2.7.1.137 | 0.000012 |
- |
Wortmannin |
specific irreversible inhibition, binds covalently to the active site, mixed type inhibition, IC50 is 12 nM |
660688 |
| 2.7.1.137 | 0.000018 |
- |
PIK-III |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.000025 |
- |
Vps34-IN-1 |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.000036 |
- |
3-Methyladenine |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.000488 |
- |
PI-103 |
pH and temperature not specified in the publication |
760521 |
| 2.7.1.137 | 0.0011 |
- |
LY294002 |
IC50 is 0.0011 mM for the recombinant wild-type enzyme and for the recombinant mutant C838V/I848A |
661328 |
