EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.1.1.37 | 0.0003 |
- |
S-adenosyl-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.0003 |
- |
S-Tubercidinylhomocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.0006 |
- |
S-(N-(2-biphenyl-4-ylethyl)adenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.0006 |
- |
S-(N-phenylpropyladenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.0009 |
- |
S-(N-(3,5-dimethoxybenzyl)adenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.001 |
- |
2-amino-4-([[(2S,3S,4R,5R)-5-(6-amino-2-methyl-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl]sulfanyl)butanoic acid |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.001 |
- |
S-(N-benzyladenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.0015 |
- |
S-Tubercidinylhomocysteine |
isoform DNMT1, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.002 |
- |
S-(N-phenyladenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |
2.1.1.37 | 0.002 |
- |
S-(N-phenylethyladenosyl)-L-homocysteine |
isoform DNMT3b2, in 50 mM Tris-HCl pH 7.6, 5% (v/v) glycerol, 1 mM EDTA, 0.1 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C |
702568 |