EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.1.1.25 | 0.002 |
- |
epicatechin gallate |
pH 8.8, 25°C, recombinant enzyme, AroE domain of the DQD-SDH enzyme |
740771 |
| 1.1.1.25 | 0.0021 |
- |
epigallocatechin gallate |
pH 8.8, 25°C, recombinant enzyme, AroE domain of the DQD-SDH enzyme |
740771 |
| 1.1.1.25 | 0.0029 |
- |
2-([2-([2-([2-(2,3-dimethylanilino)-2-oxoethyl]sulfanyl)-1,3-benzothiazol-6-yl]amino)2-oxoethyl]sulfanyl)-N-(2-naphthyl)acetamide |
IC50: 0.0029 mM, competitive inhibition with respect to shikimate, noncompetitive to NADP+, potent antibacterial activity |
668576 |
| 1.1.1.25 | 0.003 |
- |
epigallocatechin gallate |
pH 8.8, 25°C, recombinant enzyme |
740771 |
| 1.1.1.25 | 0.0035 |
- |
maesaquinone diacetate |
IC50: 0.0035 mM, noncompetitive inhibition with respect to shikimate and NADP+ |
668576 |
| 1.1.1.25 | 0.0037 |
- |
epicatechin gallate |
pH 8.8, 25°C, recombinant enzyme |
740771 |
| 1.1.1.25 | 0.0039 |
- |
3-(2-naphthyloxy)-4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl 3-chlorobenzoate |
IC50: 0.0039 mM, noncompetitive inhibition with respect to shikimate, competitive to NADP+ |
668576 |
| 1.1.1.25 | 0.0098 |
- |
epigallocatechin gallate |
pH 8.8, temperature not specified in the publication |
740978 |
| 1.1.1.25 | 0.0134 |
- |
butyl 2-([3-(2-naphthyloxy)4-oxo-2-(trifluoromethyl)4H-chromen-7-yl]oxy)propanoate |
IC50: 0.0134 mM, noncompetitive inhibition with respect to shikimate, competitive to NADP+, potent antibacterial activity |
668576 |
| 1.1.1.25 | 0.0154 |
- |
curcumin |
IC50: 0.0154 mM, noncompetitive inhibition with respect to shikimate and NADP+ |
668576 |
