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EC Number	IC50 Value	IC50 Value Maximum	Inhibitor	Commentary	Reference
2.5.1.21	0.00013	-	CP-294838	a benzoxazepinone IC50 130 nM	489849
2.5.1.21	0.00002	-	CP-295697	a bisphosphonate, IC50: 20 nM	489849
2.5.1.21	0.0000007	-	zaragozic acid	IC50 0.7 nM	489849
2.5.1.21	0.00000084	-	E5700	IC50: 0.84 nM	671377
2.5.1.21	0.0015	-	(3R)-3-[[3-(benzyloxy)phenyl]ethynyl]-1-azabicyclo[2.2.2]octan-3-ol	IC50: 1500 nM	671377
2.5.1.21	0.00000352	-	ER119884	IC50: 3.52 nM	671377
2.5.1.21	0.00005	-	ethyl 4-(1-azabicyclo[2.2.2]oct-2-en-3-yl)benzoate	IC50: 50 nM	671377
2.5.1.21	0.00073	-	3-(biphenyl-4-ylmethyl)-1-azabicyclo[2.2.2]oct-2-ene	IC50: 730 nM	671377
2.5.1.21	0.00083	-	3-[[4-(benzyloxy)phenyl]ethynyl]-1-azabicyclo[2.2.2]oct-2-ene	IC50: 830 nM	671377
2.5.1.21	0.0000955	-	zaragozic acid A	pH 7.2, 37°C	687416

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Release 2023.1 (January 2023)