EC Number   |
|---|
   4.1.3.44 | sitting drop vapor diffusion method, using 100 mM KH2PO4/Na2HPO4 pH 6.2, 10% (w/v) PEG 3000 |
| 4.1.3.44 | to 2.2 A resolution. The overall structure is a half-barrel structure, composed of six alpha-helices packed against a ten-stranded beta-sheet. Other alpha-helices and two long loops form the walls on both sides of the half-barrel. Construction of a docking model with the FeS clusters, AdoMet and the tRNA |
| 4.1.3.44 | to 2.4 A resolution. Enzyme TYW1 assumes an incomplete TIM barrel with (alpha/beta)6 topology, which closely resembles the reported structures of radical SAM enzymes. TYW1 is considered to catalyze the cyclization reaction by utilizing the radical intermediate. construction of a model structure complexed with S-adenosylmethionine and two [4Fe-4S] clusters |
