EC Number |
Reference |
---|
3.2.2.17 | - |
170697, 170703, 171807, 171808, 171809, 171813 |
3.2.2.17 | 2 amino acids critical for T4-PDG catalysis, Thr2 and Glu23, known from x-ray crystal structure studies |
171812 |
3.2.2.17 | crystallized at 15°C by the hanging-drop vapor-diffusion method, co-crystal structure of T4-Pdg as a reduced covalent complex with an AP site-containing duplex oligodeoxynucleotide. This high-resolution structure reveals essential precatalytic and catalytic features, including flipping of the nucleotide opposite the AP site, a sharp kink (about 66°) in the DNA at the dimer site and the covalent bond linking the enzyme to the DNA |
681394 |