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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.137-
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.137hanging drop vapor diffusion method, using 20% (w/v) polyethylene glycol 3000, 0.1 M Tris-HCl, pH 7.0, containing 0.2 M calcium acetate
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.137homology modeling of structure. The two conserved cysteine residues Cys145 and Cys195 are in close propinquity and form an As(III) binding site. GSH forms the third ligand with As with the sulfur atom of GSH orienting toward the bound As(III) at approximately 2.4 A distance
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.137structure with the bound aromatic arsenicals phenylarsenite at 1.80 A resolution and reduced roxarsone at 2.25 A resolution. Compounds are bound to conserved residues C174 and C224. A loop containing Cys44 and Cys72 shifts by nearly 6.5 A in the arsenic(III)-bound structures compared with the SAM-bound structure
Results 1 - 4 of 4